Cheap flights from Cali to Panama City from R3 462

The month of May is, on average, the cheapest month to fly to Panama City from Cali, with most prices found around R3 527. If you aren’t able to travel during the month of May, then book flights to Panama City from Cali during November instead. Flights to Panama City in November, while not as cheap as those in May, still average around R3 674.

You are more likely to see cheaper flights to Panama City from Cali when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around R4 086 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Cali for as low as R3 332 on momondo.

Historically, on average around 3% of flights between Cali and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 99 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights departing in the evening have, in the past, seen delays more frequently in comparison.

Monday is statistically the day of the week that experiences the fewest delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the fewest delays on this route over the last 12 months, with about 3% of their flights experiencing any sort of delay.

The number of flights available between Cali and Panama City is 8 per day as of September 2026. The most frequent departure time is 15:00, with 58% of daily flights leaving in the afternoon.

As of September 2026, 61 flights take off from Cali and land in Panama City each week. The most common flight departure day for this route is Wed, with 18% of weekly flights taking off on this day.