Cheap flights from Cali to Panama City from R5 473

The month of November is, on average, the cheapest month to fly to Panama City from Cali, with most prices found around R3 543. If you aren’t able to travel during the month of November, then book flights to Panama City from Cali during May instead. Flights to Panama City in May, while not as cheap as those in November, still average around R3 610.

You are more likely to see cheaper flights to Panama City from Cali when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around R4 309 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Cali for as low as R3 394 on momondo.

Historically, on average around 3% of flights between Cali and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 100 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights departing in the evening have, in the past, seen delays more frequently in comparison.

Monday is statistically the day of the week that experiences the fewest delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the fewest delays on this route over the last 12 months, with about 3% of their flights experiencing any sort of delay.

The number of flights available between Cali and Panama City is 10 per day as of November 2026. The most frequent departure time is 15:00, with 58% of daily flights leaving in the afternoon.

As of November 2026, 73 flights take off from Cali and land in Panama City each week. The most common flight departure day for this route is Mon, with 18% of weekly flights taking off on this day.