Cheap flights from Antofagasta to Santiago from R399

The cheapest month to fly to Santiago from Antofagasta is in September. Flight prices, which tend to average around R1 463, are often lower during this time because this is during the off-season. If you are unable to visit Santiago during the month of September, then departing from Antofagasta during the month October is also very affordable. Most momondo users find prices during this month for around R1 480.

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You are more likely to see cheaper flights to Santiago from Antofagasta when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around R1 647 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Antofagasta for as low as R998 on momondo.

There is only 1 cabin class available to choose from on Antofagasta to Santiago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Historically, on average around 11% of flights between Antofagasta and Santiago have experienced a delay on any given week. The average delay length over the past 12 months has been 98 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights departing in the evening have, in the past, seen delays more frequently in comparison.

Saturday is statistically the day of the week that experiences the fewest delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

According to our data, Sky Airline have had the fewest delays on this route over the last 12 months, with about 9% of their flights experiencing any sort of delay.

As of October 2026, there are 3 flights per day flying from Antofagasta to Santiago. The most common time of day flights depart is 8:00, with 45% of flights taking off in the evening.

As of October 2026, there are 24 flights per week flying from Antofagasta to Santiago. The most common day of the week flights depart is Wed, with 96% of flights taking off on this day.