What is the cheapest airline that flies from Panama City Tocumen Intl to Santo Domingo Las Americas?

Copa Airlines and Delta are the most popular carriers operating from Panama City Tocumen Intl to Santo Domingo Las Americas

How often are flights from Panama City to Santo Domingo delayed?

Historically, on average around 5% of flights between Panama City and Santo Domingo have experienced a delay on any given week. The average delay length over the past 12 months has been 108 minutes.

What day of the week experiences the fewest flight delays on this route?

Thursday is statistically the day of the week that experiences the fewest delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

Which airline has the best punctuality record on Panama City to Santo Domingo flights?

According to our data, Copa Airlines have had the fewest delays on this route over the last 12 months, with about 5% of their flights experiencing any sort of delay.

How many flights depart from Panama City to Santo Domingo on average per day?

4 flights are operational daily from Panama City to Santo Domingo as of September 2026. The most popular departure time for this route is 19:00, with 50% of flights per day taking off in the evening.

What is the most punctual flight time for Panama City to Santo Domingo flights?

Generally, flights departing at night tend to experience fewer delays. Flights departing in the early afternoon have, in the past, seen delays more frequently in comparison.

How many flights depart from Panama City to Santo Domingo on average per week?

As of September 2026, there are 28 flights per week flying from Panama City to Santo Domingo. The most common day of the week flights depart is Wed, with 32% of flights taking off on this day.

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

Prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport were last updated today.

How old do you have to be to fly from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and stopovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport.

What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's licence and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

R4 518 Cheap Flights from Panama City to Santo Domingo in 2026

Find the cheapest flights from Panama City to Santo Domingo

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Enter your travel dates to find the best prices.

9:42 - 13:13PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

2h 31mdirect

14:16 - 15:49SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

2h 33mdirect

R7 882Copa Airlines

Fri, Sep 25 - Wed, Sep 30

4:25 - 17:55PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

12h 30m1 stop Bogotá El Dorado

18:50 - 0:35SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

6h 45m1 stop Bogotá El Dorado

R7 898Avianca

Sun, Sep 20 - Fri, Sep 25

8:15 - 11:45PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

2h 30mdirect

8:55 - 10:30SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

2h 35mdirect

R8 507Copa Airlines

Sun, Nov 1 - Wed, Nov 4

7:39 - 11:09PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

2h 30mdirect

12:45 - 14:21SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

2h 36mdirect

R8 843Copa Airlines

Thu, Oct 29 - Fri, Nov 6

22:41 - 2:08PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

2h 27mdirect

14:19 - 15:58SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

2h 39mdirect

R9 148Copa Airlines

Sat, Dec 19 - Sat, Jan 16

9:42 - 13:08PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

2h 26mdirect

12:42 - 14:21SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

2h 39mdirect

R13 425Copa Airlines

Thu, Jan 7 - Sat, Jan 9

5:30 - 17:55PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

11h 25m2 stops San Salvador El Salvador Intl Bogotá El Dorado

18:50 - 10:30SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

16h 40m2 stops Bogotá El Dorado San Salvador El Salvador Intl

R17 767Avianca

Sun, Sep 20 - Fri, Sep 25

8:55 - 15:06PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

29h 11m2 stops Houston George Bush Intcntl Newark

6:00 - 20:02SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

15h 02m1 stop Newark

R18 471United Airlines

Sun, Nov 1 - Thu, Nov 5

8:55 - 23:46PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

37h 51m2 stops Houston George Bush Intcntl Newark

14:53 - 14:45SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

24h 52m2 stops Newark Houston George Bush Intcntl

R18 952United Airlines

Sun, Nov 1 - Thu, Nov 5

10:00 - 11:55PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

24h 55m2 stops Houston George Bush Intcntl Newark

15:20 - 18:37SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

28h 17m2 stops Newark Houston George Bush Intcntl

R22 893United Airlines

Tue, Sep 15 - Sat, Sep 19

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Avianca flights from Panama City to Santo Domingo

Our best Avianca deals on Panama City to Santo Domingo flight tickets

Avianca

Sept 20

PTY4:25Panama City Tocumen Intl

12h 30m

1 stop

SDQ17:55Santo Domingo Las Americas

Sept 25

SDQ18:50Santo Domingo Las Americas

6h 45m

1 stop

PTY0:35Panama City Tocumen Intl

R7 898

Avianca

Sept 20

PTY5:30Panama City Tocumen Intl

11h 25m

2 stops

SDQ17:55Santo Domingo Las Americas

Sept 25

SDQ18:50Santo Domingo Las Americas

16h 40m

2 stops

PTY10:30Panama City Tocumen Intl

R17 767

Copa Airlines flights from Panama City to Santo Domingo

Our best Copa Airlines deals on Panama City to Santo Domingo flight tickets

Copa Airlines

Sept 25

PTY9:42Panama City Tocumen Intl

2h 31m

SDQ13:13Santo Domingo Las Americas

Sept 30

SDQ14:16Santo Domingo Las Americas

2h 33m

PTY15:49Panama City Tocumen Intl

R7 882

Copa Airlines

Nov 1

PTY8:15Panama City Tocumen Intl

2h 30m

SDQ11:45Santo Domingo Las Americas

Nov 7

SDQ19:06Santo Domingo Las Americas

2h 34m

PTY20:40Panama City Tocumen Intl

R8 507

Copa Airlines

Oct 29

PTY7:39Panama City Tocumen Intl

2h 30m

SDQ11:09Santo Domingo Las Americas

Nov 6

SDQ12:45Santo Domingo Las Americas

2h 36m

PTY14:21Panama City Tocumen Intl

R8 843

momondo Fare Finder

Use the filters below to find and compare flights from Panama City to Santo Domingo that are best for you.

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Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Fri 25/9

9:42-13:13

Nonstop2h 31m

Santo Domingo Las Americas

Wed 30/9

14:16-15:49

Nonstop2h 33m

R7 882

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sun 20/9

4:25-17:55

1 stop12h 30m

Santo Domingo Las Americas

Fri 25/9

18:50-0:35

1 stop6h 45m

R7 898

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sun 1/11

8:15-11:45

Nonstop2h 30m

Santo Domingo Las Americas

Wed 4/11

8:55-10:30

Nonstop2h 35m

R8 507

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Thu 29/10

7:39-11:09

Nonstop2h 30m

Santo Domingo Las Americas

Fri 6/11

12:45-14:21

Nonstop2h 36m

R8 843

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sat 19/12

22:41-2:08

Nonstop2h 27m

Santo Domingo Las Americas

Sat 16/1

14:19-15:58

Nonstop2h 39m

R9 148

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Thu 7/1

9:42-13:08

Nonstop2h 26m

Santo Domingo Las Americas

Sat 9/1

12:42-14:21

Nonstop2h 39m

R13 425

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sun 20/9

5:30-17:55

2 stops11h 25m

Santo Domingo Las Americas

Fri 25/9

18:50-10:30

2 stops16h 40m

R17 767

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sun 1/11

8:55-15:06

2 stops29h 11m

Santo Domingo Las Americas

Thu 5/11

6:00-20:02

1 stop15h 02m

R18 471

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sun 1/11

8:55-23:46

2 stops37h 51m

Santo Domingo Las Americas

Thu 5/11

14:53-14:45

2 stops24h 52m

R18 952

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Tue 15/9

10:00-11:55

2 stops24h 55m

Santo Domingo Las Americas

Sat 19/9

15:20-18:37

2 stops28h 17m

R22 893

Flights are sorted by cheapest return flights first.

Showing 1-10 of 18 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Delays

Other information

What is the typical price of a round-trip flight between Panama City and Santo Domingo?

Prices are currently typical for flights on this route.

Typical prices usually range from R7 193 to R8 795.
The lowest price recently found on this route was R7 882.

What is the cheapest month to fly to Santo Domingo?

If you aren’t able to travel to Santo Domingo during the month of January, then flying in February is also cheap. Prices for this month can be found on momondo for an average of R7 257.

How far in advance should I book a flight from Panama City to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around R7 938 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Panama City for as low as R7 433 on momondo.

How have Panama City to Santo Domingo flight prices changed over time?

As of September 2026, prices for Panama City to Santo Domingo flights are approximately 25% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.

Estimated return price

Cheap Panama City to Santo Domingo (PTY to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Santo Domingo

Best price found	R4 518
Direct flights	Mon, Thu, Fri, Sat and Sun
Airports in Santo Domingo	1 airport

The best one-way flight to Santo Domingo from Panama City in the past 72 hours is R4 518. The best return flight deal from Panama City to Santo Domingo found on momondo in the last 72 hours is R7 882.

Direct flights go from Panama City to Santo Domingo on Monday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights..

There is 1 airport in Santo Domingo. From Panama City there are direct flights to Santo Domingo Las Americas (SDQ).

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Frequently asked questions about flying from Panama City to Santo Domingo

How far is Panama City Tocumen Intl to Santo Domingo Las Americas by plane?
A flight from Panama City Tocumen Intl to Santo Domingo Las Americas will travel around 1477,8 km.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?
Prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport were last updated today.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and stopovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport.
What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?
The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's licence and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Panama City to Santo Domingo?
momondo data reveals that the most frequently booked plane model on the route from Panama City to Santo Domingo is Boeing 737-800, representing 36,95% of all bookings. The subsequent popular models are Boeing 737 MAX 8 at 34,32%, Boeing 737-700 at 18,93%, and Boeing 737 MAX 9 at 9,38%.

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to Santo Domingo for you.

Can I find flights from Panama City to Santo Domingo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Santo Domingo flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Santo Domingo?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Panama City to Santo Domingo.

I’m not ready to book a flight from Panama City to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from Panama City to Santo Domingo from R4 518

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Santo Domingo departing on 11/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Avianca flights from Panama City to Santo Domingo

Our best Avianca deals on Panama City to Santo Domingo flight tickets

Copa Airlines flights from Panama City to Santo Domingo

Our best Copa Airlines deals on Panama City to Santo Domingo flight tickets

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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Panama City to Santo Domingo

What is the typical price of a round-trip flight between Panama City and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

How far in advance should I book a flight from Panama City to Santo Domingo?

How have Panama City to Santo Domingo flight prices changed over time?

What is the cheapest airline that flies from Panama City Tocumen Intl to Santo Domingo Las Americas?

How often are flights from Panama City to Santo Domingo delayed?

What is the most punctual flight time for Panama City to Santo Domingo flights?

What day of the week experiences the fewest flight delays on this route?

Which airline has the best punctuality record on Panama City to Santo Domingo flights?

How many flights depart from Panama City to Santo Domingo on average per day?

How many flights depart from Panama City to Santo Domingo on average per week?

When to book flights from Panama City to Santo Domingo

Cheap Panama City to Santo Domingo (PTY to SDQ) flight deals and tips

Best price found

Direct flights

Airports in Santo Domingo

Frequently asked questions about flying from Panama City to Santo Domingo

Why use momondo?

An easier way to manage your Santo Domingo trip

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