How many flights depart from Panama City to Santo Domingo on average per week?

As of September 2026, there are 33 flights per week flying from Panama City to Santo Domingo. The most common day of the week flights depart is Wed, with 24% of flights taking off on this day.

How many flights depart from Panama City to Santo Domingo on average per day?

4 flights are operational daily from Panama City to Santo Domingo as of September 2026. The most popular departure time for this route is 19:00, with 46% of flights per day taking off in the evening.

How often are flights from Panama City to Santo Domingo delayed?

Historically, on average around 5% of flights between Panama City and Santo Domingo have experienced a delay on any given week. The average delay length over the past 12 months has been 112 minutes.

Which airline has the best punctuality record on Panama City to Santo Domingo flights?

According to our data, Copa Airlines have had the fewest delays on this route over the last 12 months, with about 5% of their flights experiencing any sort of delay.

What is the most punctual flight time for Panama City to Santo Domingo flights?

Generally, flights departing at night tend to experience fewer delays. Flights departing in the early afternoon have, in the past, seen delays more frequently in comparison.

What is the cheapest airline that flies from Panama City Tocumen Intl to Santo Domingo Las Americas?

Copa Airlines and United Airlines are the most popular carriers operating from Panama City Tocumen Intl to Santo Domingo Las Americas

What day of the week experiences the fewest flight delays on this route?

Thursday is statistically the day of the week that experiences the fewest delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

Prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport were last updated today.

How old do you have to be to fly from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and stopovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport.

What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's licence and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

R4 584 Cheap Flights from Panama City to Santo Domingo in 2026/27

Find the cheapest flights from Panama City to Santo Domingo

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One-way

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Cheap return flights

Enter your travel dates to find the best prices.

9:42 - 13:10PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

2h 28mdirect

8:55 - 10:30SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

2h 35mdirect

R7 998Copa Airlines

Mon, Nov 2 - Mon, Nov 9

22:55 - 2:25PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

2h 30mdirect

14:16 - 15:49SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

2h 33mdirect

R8 160Copa Airlines

Sat, Oct 3 - Mon, Oct 12

12:44 - 16:13PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

2h 29mdirect

12:42 - 14:21SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

2h 39mdirect

R8 632Copa Airlines

Wed, Dec 2 - Tue, Jan 5

22:41 - 2:08PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

2h 27mdirect

14:19 - 15:58SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

2h 39mdirect

R9 282Copa Airlines

Sat, Dec 19 - Sat, Jan 16

7:24 - 10:54PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

2h 30mdirect

12:42 - 14:15SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

2h 33mdirect

R9 575Copa Airlines

Sat, Oct 3 - Mon, Oct 12

9:42 - 13:08PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

2h 26mdirect

19:05 - 20:40SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

2h 35mdirect

R13 622Copa Airlines

Sun, Jan 24 - Sun, Jan 24

8:55 - 15:06PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

29h 11m2 stops Houston George Bush Intcntl Newark

6:00 - 20:02SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

15h 02m1 stop Newark

R16 808United Airlines

Sat, Nov 14 - Sat, Nov 21

8:55 - 15:06PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

29h 11m2 stops Houston George Bush Intcntl Newark

6:00 - 20:02SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

15h 02m1 stop Newark

R17 215United Airlines

Tue, Nov 3 - Thu, Nov 12

10:00 - 23:46PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

12h 46m1 stop Newark

14:53 - 14:45SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

24h 52m2 stops Newark Houston George Bush Intcntl

R17 507United Airlines

Sun, Nov 1 - Thu, Nov 5

11:35 - 13:41PTY Panama City Tocumen Intl-SDQ Santo Domingo Las Americas

25h 06m2 stops Houston George Bush Intcntl Newark

14:53 - 20:02SDQ Santo Domingo Las Americas-PTY Panama City Tocumen Intl

30h 09m1 stop Newark

R17 572United Airlines

Wed, Dec 2 - Thu, Dec 10

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United Airlines flights from Panama City to Santo Domingo

Our best United Airlines deals on Panama City to Santo Domingo flight tickets

United Airlines

Nov 14

PTY8:55Panama City Tocumen Intl

29h 11m

2 stops

SDQ15:06Santo Domingo Las Americas

Nov 21

SDQ6:00Santo Domingo Las Americas

15h 02m

1 stop

PTY20:02Panama City Tocumen Intl

R16 808

United Airlines

Nov 3

PTY8:55Panama City Tocumen Intl

29h 11m

2 stops

SDQ15:06Santo Domingo Las Americas

Nov 12

SDQ6:00Santo Domingo Las Americas

15h 02m

1 stop

PTY20:02Panama City Tocumen Intl

R17 215

United Airlines

Nov 1

PTY10:00Panama City Tocumen Intl

12h 46m

1 stop

SDQ23:46Santo Domingo Las Americas

Nov 5

SDQ14:53Santo Domingo Las Americas

24h 52m

2 stops

PTY14:45Panama City Tocumen Intl

R17 507

Avianca flights from Panama City to Santo Domingo

Our best Avianca deals on Panama City to Santo Domingo flight tickets

Avianca

Sept 25

PTY10:10Panama City Tocumen Intl

6h 45m

1 stop

SDQ17:55Santo Domingo Las Americas

Sept 27

SDQ12:45Santo Domingo Las Americas

12h 50m

1 stop

PTY0:35Panama City Tocumen Intl

R7 965

Avianca

Sept 24

PTY17:55Panama City Tocumen Intl

16h 55m

1 stop

SDQ11:50Santo Domingo Las Americas

Sept 27

SDQ18:50Santo Domingo Las Americas

15h 25m

1 stop

PTY9:15Panama City Tocumen Intl

R8 014

Avianca

Sept 24

PTY4:25Panama City Tocumen Intl

12h 30m

1 stop

SDQ17:55Santo Domingo Las Americas

Mar 24

SDQ12:45Santo Domingo Las Americas

13h 35m

1 stop

PTY1:20Panama City Tocumen Intl

R8 632

momondo Fare Finder

Use the filters below to find and compare flights from Panama City to Santo Domingo that are best for you.

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Depart

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Price

Cheapest return flight

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Mon 2/11

9:42-13:10

Nonstop2h 28m

Santo Domingo Las Americas

Mon 9/11

8:55-10:30

Nonstop2h 35m

R7 998

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sat 3/10

22:55-2:25

Nonstop2h 30m

Santo Domingo Las Americas

Mon 12/10

14:16-15:49

Nonstop2h 33m

R8 160

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Wed 2/12

12:44-16:13

Nonstop2h 29m

Santo Domingo Las Americas

Tue 5/1

12:42-14:21

Nonstop2h 39m

R8 632

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sat 19/12

22:41-2:08

Nonstop2h 27m

Santo Domingo Las Americas

Sat 16/1

14:19-15:58

Nonstop2h 39m

R9 282

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sat 3/10

7:24-10:54

Nonstop2h 30m

Santo Domingo Las Americas

Mon 12/10

12:42-14:15

Nonstop2h 33m

R9 575

Fastest return journey

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sun 24/1

9:42-13:08

Nonstop2h 26m

Santo Domingo Las Americas

Sun 24/1

19:05-20:40

Nonstop2h 35m

R13 622

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sat 14/11

8:55-15:06

2 stops29h 11m

Santo Domingo Las Americas

Sat 21/11

6:00-20:02

1 stop15h 02m

R16 808

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Tue 3/11

8:55-15:06

2 stops29h 11m

Santo Domingo Las Americas

Thu 12/11

6:00-20:02

1 stop15h 02m

R17 215

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sun 1/11

10:00-23:46

1 stop12h 46m

Santo Domingo Las Americas

Thu 5/11

14:53-14:45

2 stops24h 52m

R17 507

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Wed 2/12

11:35-13:41

2 stops25h 06m

Santo Domingo Las Americas

Thu 10/12

14:53-20:02

1 stop30h 09m

R17 572

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Delays

Other information

What is the typical price of a round-trip flight between Panama City and Santo Domingo?

Prices are currently typical for flights on this route.

Typical prices usually range from R7 981 to R8 924.
The lowest price recently found on this route was R7 998.

What is the cheapest month to fly to Santo Domingo?

If you aren’t able to travel to Santo Domingo during the month of January, then flying in February is also cheap. Prices for this month can be found on momondo for an average of R7 364.

How far in advance should I book a flight from Panama City to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around R8 172 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Panama City for as low as R7 543 on momondo.

How have Panama City to Santo Domingo flight prices changed over time?

As of September 2026, prices for Panama City to Santo Domingo flights are approximately 29% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.

Estimated return price

Cheap Panama City to Santo Domingo (PTY to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Santo Domingo

Best price found	R4 584
Direct flights	Mon, Tue, Wed, Thu and Sun
Airports in Santo Domingo	1 airport

The best one-way flight to Santo Domingo from Panama City in the past 72 hours is R4 584. The best return flight deal from Panama City to Santo Domingo found on momondo in the last 72 hours is R7 998.

Direct flights go from Panama City to Santo Domingo on Monday, Tuesday, Wednesday, Thursday and Sunday. There are no airlines offering direct flights..

There is 1 airport in Santo Domingo. From Panama City there are direct flights to Santo Domingo Las Americas (SDQ).

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Frequently asked questions about flying from Panama City to Santo Domingo

How far is Panama City Tocumen Intl to Santo Domingo Las Americas by plane?
A flight from Panama City Tocumen Intl to Santo Domingo Las Americas will travel around 1477,8 km.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?
Prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport were last updated today.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and stopovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport.
What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?
The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's licence and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Panama City to Santo Domingo?
momondo data reveals that the most frequently booked plane model on the route from Panama City to Santo Domingo is Boeing 737-800, representing 36,51% of all bookings. The subsequent popular models are Boeing 737 MAX 8 at 33,28%, Boeing 737-700 at 19,37%, and Boeing 737 MAX 9 at 10,61%.

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to Santo Domingo for you.

Can I find flights from Panama City to Santo Domingo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Santo Domingo flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Santo Domingo?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Panama City to Santo Domingo.

I’m not ready to book a flight from Panama City to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from Panama City to Santo Domingo from R4 584

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Santo Domingo departing on 11/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Panama City to Santo Domingo

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Avianca flights from Panama City to Santo Domingo

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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Panama City to Santo Domingo

What is the typical price of a round-trip flight between Panama City and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

How far in advance should I book a flight from Panama City to Santo Domingo?

How have Panama City to Santo Domingo flight prices changed over time?

What is the cheapest airline that flies from Panama City Tocumen Intl to Santo Domingo Las Americas?

How often are flights from Panama City to Santo Domingo delayed?

What is the most punctual flight time for Panama City to Santo Domingo flights?

What day of the week experiences the fewest flight delays on this route?

Which airline has the best punctuality record on Panama City to Santo Domingo flights?

How many flights depart from Panama City to Santo Domingo on average per day?

How many flights depart from Panama City to Santo Domingo on average per week?

When to book flights from Panama City to Santo Domingo

Cheap Panama City to Santo Domingo (PTY to SDQ) flight deals and tips

Best price found

Direct flights

Airports in Santo Domingo

Frequently asked questions about flying from Panama City to Santo Domingo

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