Cheap flights from Panama City to Santo Domingo from R8 884

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1 adult, Economy, 0 bags

Find the cheapest flights from Panama City to Santo Domingo

Cheap return flights

Enter your travel dates to find the best prices.
Avianca Logo
2:30 - 17:50PTY  Panama City Tocumen Intl-SDQ Santo Domingo Las Americas
14h 20m1 stop Bogotá El Dorado
Avianca Logo
12:45 - 17:15SDQ  Santo Domingo Las Americas-PTY Panama City Tocumen Intl
5h 30m1 stop Bogotá El Dorado
R8 884Avianca
Wed, Dec 2 - Sat, Dec 12
Avianca Logo
2:30 - 11:50PTY  Panama City Tocumen Intl-SDQ Santo Domingo Las Americas
8h 20m1 stop Bogotá El Dorado
Avianca Logo
12:45 - 17:15SDQ  Santo Domingo Las Americas-PTY Panama City Tocumen Intl
5h 30m1 stop Bogotá El Dorado
R8 983Avianca
Tue, Jan 19 - Sat, Jan 23
Copa Airlines Logo
7:39 - 11:02PTY  Panama City Tocumen Intl-SDQ Santo Domingo Las Americas
2h 23mdirect
Copa Airlines Logo
14:19 - 15:58SDQ  Santo Domingo Las Americas-PTY Panama City Tocumen Intl
2h 39mdirect
R9 412Copa Airlines
Sat, Dec 19 - Fri, Jan 15
Copa Airlines Logo
19:26 - 22:58PTY  Panama City Tocumen Intl-SDQ Santo Domingo Las Americas
2h 32mdirect
Copa Airlines Logo
19:06 - 20:40SDQ  Santo Domingo Las Americas-PTY Panama City Tocumen Intl
2h 34mdirect
R9 593Copa Airlines
Fri, Nov 20 - Sun, Nov 22
Copa Airlines Logo
7:40 - 11:07PTY  Panama City Tocumen Intl-SDQ Santo Domingo Las Americas
2h 27mdirect
Copa Airlines Logo
12:42 - 14:21SDQ  Santo Domingo Las Americas-PTY Panama City Tocumen Intl
2h 39mdirect
R9 725Copa Airlines
Tue, Nov 24 - Mon, Jan 4
Copa Airlines Logo
19:26 - 22:58PTY  Panama City Tocumen Intl-SDQ Santo Domingo Las Americas
2h 32mdirect
Copa Airlines Logo
5:50 - 7:28SDQ  Santo Domingo Las Americas-PTY Panama City Tocumen Intl
2h 38mdirect
R10 121Copa Airlines
Tue, Dec 22 - Tue, Jan 5
Avianca Logo
10:05 - 17:50PTY  Panama City Tocumen Intl-SDQ Santo Domingo Las Americas
6h 45m1 stop Bogotá El Dorado
Avianca Logo
12:45 - 17:15SDQ  Santo Domingo Las Americas-PTY Panama City Tocumen Intl
5h 30m1 stop Bogotá El Dorado
R10 170Avianca
Thu, Nov 26 - Sun, Nov 29
Copa Airlines Logo
19:26 - 22:58PTY  Panama City Tocumen Intl-SDQ Santo Domingo Las Americas
2h 32mdirect
Copa Airlines Logo
12:06 - 13:45SDQ  Santo Domingo Las Americas-PTY Panama City Tocumen Intl
2h 39mdirect
R10 384Copa Airlines
Sun, Dec 27 - Thu, Jan 14
Copa Airlines Logo
12:44 - 16:13PTY  Panama City Tocumen Intl-SDQ Santo Domingo Las Americas
2h 29mdirect
Copa Airlines Logo
5:50 - 7:28SDQ  Santo Domingo Las Americas-PTY Panama City Tocumen Intl
2h 38mdirect
R10 434Copa Airlines
Wed, Dec 23 - Sun, Jan 3
Copa Airlines Logo
23:34 - 2:57PTY  Panama City Tocumen Intl-SDQ Santo Domingo Las Americas
2h 23mdirect
Copa Airlines Logo
10:58 - 12:40SDQ  Santo Domingo Las Americas-PTY Panama City Tocumen Intl
2h 42mdirect
R10 615Copa Airlines
Mon, May 3 - Sat, May 8

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Avianca flights from Panama City to Santo Domingo

Our best Avianca deals on Panama City to Santo Domingo flight tickets
Avianca
Dec 2
PTY2:30Panama City Tocumen Intl
14h 20m
1 stop
SDQ17:50Santo Domingo Las Americas
Dec 12
SDQ12:45Santo Domingo Las Americas
5h 30m
1 stop
PTY17:15Panama City Tocumen Intl
R8 884
Avianca
Jan 19
PTY2:30Panama City Tocumen Intl
8h 20m
1 stop
SDQ11:50Santo Domingo Las Americas
Jan 23
SDQ12:45Santo Domingo Las Americas
5h 30m
1 stop
PTY17:15Panama City Tocumen Intl
R8 983
Avianca
Nov 26
PTY10:05Panama City Tocumen Intl
6h 45m
1 stop
SDQ17:50Santo Domingo Las Americas
Nov 29
SDQ12:45Santo Domingo Las Americas
5h 30m
1 stop
PTY17:15Panama City Tocumen Intl
R10 170

Copa Airlines flights from Panama City to Santo Domingo

Our best Copa Airlines deals on Panama City to Santo Domingo flight tickets
Copa Airlines
Dec 19
PTY7:39Panama City Tocumen Intl
2h 23m
SDQ11:02Santo Domingo Las Americas
Jan 15
SDQ14:19Santo Domingo Las Americas
2h 39m
PTY15:58Panama City Tocumen Intl
R9 412
Copa Airlines
Nov 20
PTY19:26Panama City Tocumen Intl
2h 32m
SDQ22:58Santo Domingo Las Americas
Nov 22
SDQ19:06Santo Domingo Las Americas
2h 34m
PTY20:40Panama City Tocumen Intl
R9 593
Copa Airlines
Nov 24
PTY7:40Panama City Tocumen Intl
2h 27m
SDQ11:07Santo Domingo Las Americas
Jan 4
SDQ12:42Santo Domingo Las Americas
2h 39m
PTY14:21Panama City Tocumen Intl
R9 725

momondo Fare Finder

 
Use the filters below to find and compare flights from Panama City to Santo Domingo that are best for you.

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Route

Depart

Return

Price

Cheapest return flight

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Wed 2/12

2:30-17:50

1 stop14h 20m

Santo Domingo Las Americas

Sat 12/12

12:45-17:15

1 stop5h 30m

R8 884

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Tue 19/1

2:30-11:50

1 stop8h 20m

Santo Domingo Las Americas

Sat 23/1

12:45-17:15

1 stop5h 30m

R8 983
Fastest return journey

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sat 19/12

7:39-11:02

Nonstop2h 23m

Santo Domingo Las Americas

Fri 15/1

14:19-15:58

Nonstop2h 39m

R9 412

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Fri 20/11

19:26-22:58

Nonstop2h 32m

Santo Domingo Las Americas

Sun 22/11

19:06-20:40

Nonstop2h 34m

R9 593

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Tue 24/11

7:40-11:07

Nonstop2h 27m

Santo Domingo Las Americas

Mon 4/1

12:42-14:21

Nonstop2h 39m

R9 725

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Tue 22/12

19:26-22:58

Nonstop2h 32m

Santo Domingo Las Americas

Tue 5/1

5:50-7:28

Nonstop2h 38m

R10 121

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Thu 26/11

10:05-17:50

1 stop6h 45m

Santo Domingo Las Americas

Sun 29/11

12:45-17:15

1 stop5h 30m

R10 170

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sun 27/12

19:26-22:58

Nonstop2h 32m

Santo Domingo Las Americas

Thu 14/1

12:06-13:45

Nonstop2h 39m

R10 384

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Wed 23/12

12:44-16:13

Nonstop2h 29m

Santo Domingo Las Americas

Sun 3/1

5:50-7:28

Nonstop2h 38m

R10 434

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Mon 3/5

23:34-2:57

Nonstop2h 23m

Santo Domingo Las Americas

Sat 8/5

10:58-12:40

Nonstop2h 42m

R10 615

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Panama City to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Santo Domingo?

Prices are currently typical for flights on this route.

Typical prices usually range from R8 093 to R9 049.
The lowest price recently found on this route was R8 884.

What is the cheapest month to fly to Santo Domingo?

If you aren’t able to travel to Santo Domingo during the month of February, then flying in March is also cheap. Prices for this month can be found on momondo for an average of R7 797.

How far in advance should I book a flight from Panama City to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around R8 401 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Panama City for as low as R7 302 on momondo.

How have Panama City to Santo Domingo flight prices changed over time?

As of November 2026, prices for Panama City to Santo Domingo flights are approximately 8% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Panama City to Santo Domingo (PTY to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Santo Domingo

Best price found

R8 901

Direct flights

Mon, Tue, Wed, Thu, Sat and Sun

Airports in Santo Domingo

1 airport
The best one-way flight to Santo Domingo from Panama City in the past 72 hours is R8 901. The best return flight deal from Panama City to Santo Domingo found on momondo in the last 72 hours is R8 884.
Direct flights go from Panama City to Santo Domingo on Monday, Tuesday, Wednesday, Thursday, Saturday and Sunday. There are no airlines offering direct flights..
There is 1 airport in Santo Domingo. From Panama City there are direct flights to Santo Domingo Las Americas (SDQ).

Frequently asked questions about flying from Panama City to Santo Domingo

  • How far is Panama City Tocumen Intl to Santo Domingo Las Americas by plane?

    A flight from Panama City Tocumen Intl to Santo Domingo Las Americas will travel around 1477,8 km.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport were last updated today.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and stopovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's licence and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to Santo Domingo?

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to Santo Domingo for you.

Can I find flights from Panama City to Santo Domingo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Santo Domingo flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Santo Domingo?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Panama City to Santo Domingo.

I’m not ready to book a flight from Panama City to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Tue 8/12
Tue 15/12