Cheap flights from Sao Paulo to Panama City from R4 593

The month of March is, on average, the cheapest month to fly to Panama City from Sao Paulo, with most prices found around R7 512. If you aren’t able to travel during the month of March, then book flights to Panama City from Sao Paulo during June instead. Flights to Panama City in June, while not as cheap as those in March, still average around R7 971.

According to our data, Wednesday is the cheapest day to fly to Panama City from Sao Paulo. The lowest ticket price found for a Wednesday departure recently was R9 884. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around R18 597. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Flying to Panama City from Sao Paulo in the evening is the least expensive time of day to depart. momondo users have found prices as low as R13 027 when looking at flights departing in the evening. Try not to purchase tickets in the morning because they tend to be around R14 974. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Sao Paulo Guarulhos Intl to Panama City Tocumen Intl for the best Sao Paulo - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from Sao Paulo when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around R9 092 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Sao Paulo for as low as R8 496 on momondo.

There is only 1 cabin class available to choose from on Sao Paulo to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 42% on your flight if you consider stops on a Sao Paulo to Panama City flight.

As of November 2026, prices for Sao Paulo to Panama City flights are approximately 35% cheaper when compared to flights at the same time last year.

The number of flights available between Sao Paulo and Panama City is 17 per day as of November 2026. The most frequent departure time is 1:00, with 71% of daily flights leaving in the morning.

As of November 2026, there are 119 flights per week flying from Sao Paulo to Panama City. The most common day of the week flights depart is Thu, with 16% of flights taking off on this day.