Cheap flights from Cancún to Panama City from R3 850

The month of November is, on average, the cheapest month to fly to Panama City from Cancún, with most prices found around R5 254. If you aren’t able to travel during the month of November, then book flights to Panama City from Cancún during May instead. Flights to Panama City in May, while not as cheap as those in November, still average around R5 419.

You are more likely to see cheaper flights to Panama City from Cancún when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around R6 066 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Cancún for as low as R5 436 on momondo.

Historically, on average around 5% of flights between Cancún and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 100 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights departing in the early afternoon have, in the past, seen delays more frequently in comparison.

Wednesday is statistically the day of the week that experiences the fewest delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the fewest delays on this route over the last 12 months, with about 5% of their flights experiencing any sort of delay.

4 flights are operational daily from Cancún to Panama City as of October 2026. The most popular departure time for this route is 11:00, with 65% of flights per day taking off at midday.

The number of flights available between Cancún and Panama City is 28 per week as of October 2026. The most frequent departure day is Mon, with 18% of weekly flights leaving on this day.