Cheap flights from Mexico City to Panama City from R3 002

The month of February is, on average, the cheapest month to fly to Panama City from Mexico City, with most prices found around R5 922. If you aren’t able to travel during the month of February, then book flights to Panama City from Mexico City during January instead. Flights to Panama City in January, while not as cheap as those in February, still average around R6 119.

Fly from Mexico City Benito Juarez to Panama City Tocumen Intl for the best Mexico City Benito Juarez - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from Mexico City when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around R6 602 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Mexico City for as low as R6 020 on momondo.

There is only 1 cabin class available to choose from on Mexico City to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Historically, on average around 4% of flights between Mexico City and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 119 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights departing in the early afternoon have, in the past, seen delays more frequently in comparison.

Friday is statistically the day of the week that experiences the fewest delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the fewest delays on this route over the last 12 months, with about 4% of their flights experiencing any sort of delay.

As of September 2026, 8 flights take off from Mexico City and land in Panama City each day. The most common flight departure time for this route is 1:00, with 53% of daily flights taking off in the morning.

As of September 2026, 56 flights take off from Mexico City and land in Panama City each week. The most common flight departure day for this route is Wed, with 16% of weekly flights taking off on this day.