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Cheap flights from Des Moines to Johannesburg from R12 320

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Johannesburg departing on 14/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap return flights

Enter your travel dates to find the best prices.
American Airlines Logo
14:02 - 7:35
DSM
-
JNB
33h 33m2 stops
American Airlines Logo
19:35 - 18:19
JNB
-
DSM
30h 44m2 stops
R18 686American Airlines
Sun, Feb 22 - Sun, Mar 1
American Airlines Logo
13:38 - 10:25
DSM
-
JNB
36h 47m2 stops
American Airlines Logo
22:00 - 22:19
JNB
-
DSM
32h 19m2 stops
R18 703American Airlines
Sun, Feb 22 - Sun, Mar 1
Multiple Airlines Logo
14:08 - 10:25
DSM
-
JNB
36h 17m2 stops
Multiple Airlines Logo
19:35 - 17:28
JNB
-
DSM
29h 53m2 stops
R18 835Multiple Airlines
Sun, Feb 22 - Sun, Mar 1
American Airlines Logo
14:02 - 10:25
DSM
-
JNB
36h 23m2 stops
American Airlines Logo
22:00 - 18:19
JNB
-
DSM
28h 19m2 stops
R20 385American Airlines
Fri, Feb 20 - Fri, Feb 27
American Airlines Logo
14:18 - 7:00
DSM
-
JNB
33h 42m2 stops
American Airlines Logo
21:15 - 19:31
JNB
-
DSM
29h 16m2 stops
R20 418American Airlines
Thu, May 7 - Tue, May 19
American Airlines Logo
19:05 - 9:25
DSM
-
JNB
31h 20m2 stops
American Airlines Logo
19:25 - 17:59
JNB
-
DSM
29h 34m2 stops
R20 831American Airlines
Fri, May 8 - Wed, May 20
British Airways Logo
19:44 - 7:35
DSM
-
JNB
51h 51m2 stops
British Airways Logo
22:00 - 22:19
JNB
-
DSM
32h 19m2 stops
R20 929British Airways
Sun, Feb 22 - Sun, Mar 1
British Airways Logo
19:44 - 10:25
DSM
-
JNB
54h 41m2 stops
British Airways Logo
22:00 - 23:40
JNB
-
DSM
33h 40m2 stops
R21 424British Airways
Sun, Feb 22 - Sun, Mar 1
Qatar Airways Logo
19:27 - 9:00
DSM
-
JNB
30h 33m2 stops
Qatar Airways Logo
20:55 - 0:11
JNB
-
DSM
34h 16m2 stops
R21 870Qatar Airways
Sun, Apr 5 - Sun, Apr 12
American Airlines Logo
18:29 - 9:25
DSM
-
JNB
31h 56m2 stops
American Airlines Logo
19:25 - 18:25
JNB
-
DSM
30h 00m2 stops
R22 067American Airlines
Mon, Jun 15 - Wed, Jul 15

Air Canada flights from Des Moines to Johannesburg OR Tambo Airport

Our best Air Canada deals on Des Moines to Johannesburg OR Tambo Airport flight tickets
Air Canada
May 8
DSM11:30Des Moines
38h 05m
3 stops
JNB8:35Johannesburg OR Tambo
May 20
JNB19:25Johannesburg OR Tambo
32h 31m
3 stops
DSM20:56Des Moines
R29 638
Air Canada
Feb 22
DSM11:30Des Moines
38h 00m
3 stops
JNB9:30Johannesburg OR Tambo
Mar 1
JNB20:15Johannesburg OR Tambo
46h 38m
3 stops
DSM10:53Des Moines
R29 902
Air Canada
Feb 22
DSM11:30Des Moines
38h 00m
3 stops
JNB9:30Johannesburg OR Tambo
Mar 1
JNB20:15Johannesburg OR Tambo
46h 38m
3 stops
DSM10:53Des Moines
R29 951

British Airways flights from Des Moines to Johannesburg OR Tambo Airport

Our best British Airways deals on Des Moines to Johannesburg OR Tambo Airport flight tickets
British Airways
Feb 22
DSM19:44Des Moines
51h 51m
2 stops
JNB7:35Johannesburg OR Tambo
Mar 1
JNB22:00Johannesburg OR Tambo
32h 19m
2 stops
DSM22:19Des Moines
R20 929
British Airways
Feb 22
DSM19:44Des Moines
54h 41m
2 stops
JNB10:25Johannesburg OR Tambo
Mar 1
JNB22:00Johannesburg OR Tambo
33h 40m
2 stops
DSM23:40Des Moines
R21 424
British Airways
Mar 5
DSM13:38Des Moines
33h 57m
2 stops
JNB7:35Johannesburg OR Tambo
Mar 9
JNB22:00Johannesburg OR Tambo
31h 34m
2 stops
DSM22:34Des Moines
R22 298

momondo Fare Finder

 
Customise your flight search to find flights from Des Moines to Johannesburg OR Tambo Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 13 550 searches. Data last updated 9 January 2026.
Use the filters below to find and compare flights from Des Moines to Johannesburg OR Tambo Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 22/2

14:02-7:35

2 stops33h 33m

Johannesburg OR Tambo

Sun 1/3

19:35-18:19

2 stops30h 44m

R18 686

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 22/2

13:38-10:25

2 stops36h 47m

Johannesburg OR Tambo

Sun 1/3

22:00-22:19

2 stops32h 19m

R18 703

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 22/2

14:08-10:25

2 stops36h 17m

Johannesburg OR Tambo

Sun 1/3

19:35-17:28

2 stops29h 53m

R18 835

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 20/2

14:02-10:25

2 stops36h 23m

Johannesburg OR Tambo

Fri 27/2

22:00-18:19

2 stops28h 19m

R20 385

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 7/5

14:18-7:00

2 stops33h 42m

Johannesburg OR Tambo

Tue 19/5

21:15-19:31

2 stops29h 16m

R20 418

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 8/5

19:05-9:25

2 stops31h 20m

Johannesburg OR Tambo

Wed 20/5

19:25-17:59

2 stops29h 34m

R20 830

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 22/2

19:44-7:35

2 stops51h 51m

Johannesburg OR Tambo

Sun 1/3

22:00-22:19

2 stops32h 19m

R20 929

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 22/2

19:44-10:25

2 stops54h 41m

Johannesburg OR Tambo

Sun 1/3

22:00-23:40

2 stops33h 40m

R21 424

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 5/4

19:27-9:00

2 stops30h 33m

Johannesburg OR Tambo

Sun 12/4

20:55-0:11

2 stops34h 16m

R21 870

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Mon 15/6

18:29-9:25

2 stops31h 56m

Johannesburg OR Tambo

Wed 15/7

19:25-18:25

2 stops30h 00m

R22 067

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Johannesburg OR Tambo Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Johannesburg OR Tambo?

Etihad Airways, Qatar Airways, and Virgin Atlantic are the most popular carriers operating from Des Moines to Johannesburg OR Tambo

When to book flights from Des Moines to Johannesburg OR Tambo Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Johannesburg OR Tambo Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Des Moines to Johannesburg OR Tambo Airport (DSM to JNB) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Johannesburg OR Tambo Airport

Fastest flight time

28h 17m

Direct flights

None
The fastest flight from Des Moines to Johannesburg OR Tambo Airport takes 28h 17m
There are no direct flights from Des Moines to Johannesburg OR Tambo Airport. There are no popular flight routes from Des Moines to Johannesburg OR Tambo Airport.
Search flight deals

  • How far is Des Moines to Johannesburg OR Tambo by plane?

    A flight from Des Moines to Johannesburg OR Tambo will travel around 14479,0 km. 28h 17m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Johannesburg OR Tambo Airport?

    Prices for flights from Des Moines Airport to Johannesburg OR Tambo Airport were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Johannesburg OR Tambo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Johannesburg OR Tambo Airport.

  • What documentation or ID do you need to fly to Johannesburg OR Tambo Airport?

    The necessary travel and health documents for your Johannesburg OR Tambo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's licence and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Travelling to a place near Johannesburg?

Book flights to Johannesburg if you plan to visit one of these locations
Sandton
Kempton Park
Potchefstroom
Middelburg
Edenvale

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Johannesburg?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Johannesburg from Des Moines.

Can I find flights from Des Moines to Johannesburg with flexible booking policies on momondo?

Yes. All flights to Johannesburg from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Johannesburg?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Des Moines to Johannesburg.

I’m not ready to book a flight from Des Moines to Johannesburg right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Johannesburg, momondo offers a useful price alert feature which will track prices for flights to Johannesburg from Des Moines and alert you when they change.

An easier way to manage your Johannesburg OR Tambo Airport trip

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