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Travelling from most locations, it is best to book your flight to Rome during the month of May for the best deal, although there are other times of the year which offer great deals as well.
On average, from most locations, when planning your trip to Rome, try to book your flight in the region of 25 days in advance for the cheapest prices.
From most locations, the cheapest flights to Rome are found on a Wednesday. Booking a Saturday departure is usually the most expensive.
Typically, cheap prices to Rome are most often found for afternoon flights. Cheap prices are less likely for evening flights.