In general, when looking for the cheapest flight to Rome, try to choose a flight departing in May for the best deal.
From most locations, booking your flights to Rome around 18 days prior to your departure date finds the best deals.
On average, the cheapest flights to Rome are found when departing on a Wednesday. Try to avoid departing on a Saturday, as this is usually the most expensive day.
Generally, when visiting Rome, afternoon flights represent the best value. evening flights are likely to have higher prices.